Table 4.
Associations between miRNAs differentially expressed between microsatellite unstable and microsatellite stable rectal tumors with a false discovery rate set at 0.05
| Microsatellite Stable | Microsatellite Unstable | |||||
|---|---|---|---|---|---|---|
| miRNA | % Expressing | Mean Expression | % Expressing | Mean Expression | Siggenes p value | Fold Change1 |
| hsa-let-7a-5p | 99.9 | 272.16 | 100 | 160.81 | 0.010 | 0.59 |
| hsa-let-7f-5p | 99.4 | 149.04 | 100 | 81.94 | 0.010 | 0.55 |
| hsa-let-7g-5p | 99 | 52.05 | 100 | 27.61 | 0.010 | 0.53 |
| hsa-miR-100-5p | 80.8 | 9.71 | 50 | 2.56 | 0.000 | 0.26 |
| hsa-miR-125b-5p | 98.9 | 62.09 | 100 | 28.37 | 0.010 | 0.46 |
| hsa-miR-1281 | 100 | 42.21 | 100 | 63.57 | 0.010 | 1.51 |
| hsa-miR-145-5p | 100 | 133.78 | 100 | 47.27 | 0.000 | 0.35 |
| hsa-miR-151a-5p | 95.9 | 14.13 | 62.5 | 4.25 | 0.000 | 0.3 |
| hsa-miR-151b | 88.7 | 6.81 | 50 | 2.12 | 0.000 | 0.31 |
| hsa-miR-196b-5p | 77.6 | 14.95 | 37.5 | 1.33 | 0.000 | 0.09 |
| hsa-miR-199a-5p | 93.8 | 18.26 | 75 | 6.39 | 0.010 | 0.35 |
| hsa-miR-221-3p | 90.6 | 11.27 | 62.5 | 4.57 | 0.010 | 0.41 |
| hsa-miR-23a-3p | 100 | 164.28 | 100 | 83.89 | 0.000 | 0.51 |
| hsa-miR-23b-3p | 99.3 | 68.68 | 100 | 29.5 | 0.000 | 0.43 |
| hsa-miR-24-3p | 100 | 97 | 100 | 57.89 | 0.000 | 0.6 |
| hsa-miR-26a-5p | 100 | 97.29 | 100 | 40.86 | 0.000 | 0.42 |
| hsa-miR-26b-5p | 94.2 | 16.93 | 62.5 | 6.01 | 0.010 | 0.35 |
| hsa-miR-27b-3p | 98.5 | 31.49 | 87.5 | 14.04 | 0.010 | 0.45 |
| hsa-miR-29c-3p | 90.9 | 15.69 | 56.3 | 5.74 | 0.010 | 0.37 |
| hsa-miR-30b-5p | 97.6 | 21.37 | 75 | 8.42 | 0.010 | 0.39 |
| hsa-miR-30c-5p | 88.5 | 7.56 | 62.5 | 2.7 | 0.010 | 0.36 |
| hsa-miR-30d-5p | 99.9 | 31.73 | 100 | 18.7 | 0.000 | 0.59 |
| hsa-miR-3150b-5p | 97.1 | 12 | 100 | 18.48 | 0.000 | 1.54 |
| hsa-miR-331-3p | 98.8 | 13.8 | 75 | 6.55 | 0.010 | 0.47 |
| hsa-miR-361-5p | 93.5 | 11.38 | 56.3 | 2.74 | 0.000 | 0.24 |
| hsa-miR-3653 | 97.8 | 13.88 | 75 | 6.64 | 0.010 | 0.48 |
| hsa-miR-365a-3p | 74.8 | 8.09 | 37.5 | 3.27 | 0.010 | 0.4 |
| hsa-miR-424-3p | 100 | 37.2 | 100 | 23.46 | 0.010 | 0.63 |
| hsa-miR-425-5p | 89.8 | 10.87 | 62.5 | 5.37 | 0.010 | 0.49 |
| hsa-miR-4532 | 100 | 296.27 | 100 | 446.24 | 0.030 | 1.51 |
| hsa-miR-4655-3p | 98.5 | 14.89 | 100 | 22.35 | 0.010 | 1.5 |
| hsa-miR-4674 | 91 | 5.41 | 100 | 10.55 | 0.020 | 1.95 |
| hsa-miR-4769-3p | 92.3 | 7.77 | 100 | 12.21 | 0.000 | 1.57 |
| hsa-miR-520e | 94.7 | 9.87 | 100 | 15 | 0.000 | 1.52 |
| hsa-miR-5703 | 100 | 197.43 | 100 | 309.88 | 0.000 | 1.57 |
| hsa-miR-636 | 99.7 | 8.97 | 100 | 13.59 | 0.010 | 1.51 |
| hsa-miR-664b-3p | 99.9 | 33.48 | 100 | 19.84 | 0.000 | 0.59 |
| hsa-miR-664b-5p | 99.9 | 58.55 | 100 | 35.64 | 0.000 | 0.61 |
| hsa-miR-877-3p | 100 | 24.65 | 100 | 37.46 | 0.000 | 1.52 |
| hsa-miR-92a-3p | 100 | 116.97 | 100 | 58.86 | 0.000 | 0.5 |
| hsa-miR-940 | 100 | 591.89 | 100 | 895.9 | 0.010 | 1.51 |
1
Fold change is based on microsatellite unstable/microsatellite stable