Table 3. Comparison of PTEN immunohistochemistry and FISH results on tissue microarray cores and standard tissue section slides.
| Case | Tissue microarray PTEN immunohistochemistry | standard slide PTEN immunohistochemistry | Tissue microarray PTEN FISH | standard slide PTEN FISH |
|---|---|---|---|---|
| 1 | intact | intact | intact | intact |
| 2 | intact | heterogeneous loss | intact | intact |
| 3 | intact | intact | intact | intact |
| 4 | intact | intact | intact | failure |
| 5 | heterogeneous loss | heterogeneous loss | homo-deletion | hemi-deletion and homo-delletion |
| 6 | heterogeneous loss | heterogeneous loss | homo-deletion | homo-deletion |
| 7 | heterogeneous loss | heterogeneous loss | homo-deletion | homo-deletion |
| 8 | heterogeneous loss | heterogeneous loss | intact | intact |
| 9 | heterogeneous loss | heterogeneous loss | intact | intact |
| 10 | heterogeneous loss | intact | intact | intact |
| 11 | heterogeneous loss | heterogeneous loss | intact | intact |
| 12 | heterogeneous loss | intact | intact | hemi-deletion |
| 13 | heterogeneous loss | heterogeneous loss | intact | homo |
| 14 | heterogeneous loss | heterogeneous loss | intact | homo |
| 15 | heterogeneous loss | heterogeneous loss | intact | hemi-deletion of WAPAL |
| 16 | homogeneous loss | homogeneous loss | hemi-deletion | hemi-deletion |
| 17 | homogeneous loss | heterogeneous loss | intact | hemi-deletion |
| 18 | ambiguous | intact | intact | intact |
| 19 | heterogeneous loss | heterogeneous loss | core missing | intact |
| 20 | heterogeneous loss | heterogeneous loss | core missing | intact |