Table 3.
Results of Regression Analyses Examining the Associations between BMI at Age 18 and Adult Cognitive Function (Pre-Operative and 12-Month Post-Operative)
| Pre-Operative Cognitive Function | R2 | Model F (p) | Δ R2 | F Δ (p) |
|---|---|---|---|---|
| Attention | ||||
| Block 1 | ||||
| T2DM, HTN, sleep apnea | 0.02 | 0.53 (0.66) | – | – |
| Block 2 | ||||
| 0.15 | ||||
| Age difference | 0.43 (0.79) | 0.00 | ||
| (0.70) | ||||
| Block 3 | 0.02 | |||
| 0.03 | 0.40 (0.85) | 0.00 | 0.31 | |
| BMI 18 years | (0.58) | |||
| Executive function | ||||
| Block 1 | ||||
| T2DM, HTN, sleep apnea | 0.06 | 1.59 (0.20) | – | – |
| Block 2 | ||||
| Age difference | 1.20 (0.32) | 0.09 | ||
| Block 3 | 0.06 | 0.00 | (0.77) | |
| 0.06 | 0.97 (0.45) | 0.00 | 0.08 | |
| BMI 18 years | (0.77) | |||
| Memory | ||||
| Block 1 | ||||
| T2DM, HTN, sleep apnea | 0.03 | 0.72 (0.54) | – | – |
| Block 2 | ||||
| 0.17 | ||||
| Age difference | 0.03 | 0.58 (0.68) | 0.00 | |
| (0.68) | ||||
| Block 3 | ||||
| 0.03 | 0.47 (0.80) | 0.00 | 0.04 | |
| BMI 18 years | (0.84) | |||
| Verbal Fluency | ||||
| Block 1 | ||||
| T2DM, HTN, sleep apnea | 0.01 | 0.29 (0.83) | – | – |
| Block 2 | ||||
| 0.92 | ||||
| Age difference | 0.02 | 0.45 (0.77) | 0.01 | |
| (0.34) | ||||
| Block 3 | ||||
| 0.08 | 1.21 (0.31) | 0.05 | 4.17 | |
| BMI 18 years | (0.045) | |||
| 12-Month Post-Operative Cognitive Function | ||||
| Attention | ||||
| Block 1 | ||||
| BL Attention, T2DM, HTN, sleep apnea | 0.17 | 3.70 (0.01) | – | – |
| Block 2 | ||||
| 0.20 | ||||
| Age difference | 0.17 | 2.97 (0.02) | 0.00 | |
| (0.66) | ||||
| Block 3 | ||||
| 0.24 | 3.74 (<0.01) | 0.07 | 6.48 | |
| BMI 18 years | (0.01) | |||
| Executive function | ||||
| Block 1 | ||||
| BL Executive function, T2DM, HTN, sleep apnea | 0.59 | 26.23 (<0.01) | – | – |
| Block 2 | ||||
| 0.13 | ||||
| Age difference | 0.59 | 20.76 (<0.01) | 0.00 | |
| (0.73) | ||||
| Block 3 | ||||
| 0.59 | 17.07 (<0.01) | 0.00 | 0.03 | |
| BMI 18 years | (0.87) | |||
| Memory | ||||
| Block 1 | ||||
| BL Memory, T2DM, HTN, sleep apnea | 0.22 | 5.16 (<0.01) | – | – |
| Block 2 | ||||
| 1.19 | ||||
| Age difference | 0.23 | 4.37 (<0.01) | 0.01 | |
| (0.28) | ||||
| Block 3 | ||||
| 0.25 | 3.91 (<0.01) | 0.02 | 1.45 | |
| BMI 18 years | (0.23) | |||
| Verbal Fluency | ||||
| Block 1 | ||||
| BL Verbal Fluency, T2DM, HTN, sleep apnea | 0.56 | 23.37 (<0.01) | – | – |
| Block 2 | ||||
| 0.75 | ||||
| Age difference | 0.57 | 18.79 (<0.01) | 0.01 | |
| (0.39) | ||||
| Block 3 | ||||
| BMI 18 years | 0.57 | 15.44 (<0.01) | 0.00 | 0.00 |
Note. BL = baseline; T2DM = type 2 diabetes mellitus; HTN = hypertension; BMI = body mass index; BMI is continuous; age difference = difference between current age and 18.