Table 2.
Discovery timeline of antimicrobial peptides from scorpions1
Year | α-Helical peptides | β-Sheet peptides | Total AMPs per year |
---|---|---|---|
1993 | scorpion defensin (3S–S) | 1 | |
1996 | Androctonin (2S–S); Buthinin (3S- S); Androctonus (3S–S) |
3 | |
2000 | Hadrurin | Scorpine (3S–S) | 2 |
2001 | Pandinins 1 & 2; IsCT1 | 3 | |
2002 | Opistoporins 1&2; IsCT2; Parabutoporin |
4 | |
2004 | Bmkb1; BmKn2 | Charybdotoxin (3S–S); Opiscorpine 1 (3S–S) |
4 |
2007 | Heteroscorpine (3S–S) | 1 | |
2008 | Mucroporin | BmK AS (4S–S) | 2 |
2009 | Imcroporin; Meucin-13; Meucin-18; |
Bactridines 1 & 2 (4S–S) | 5 |
2010 | Im-1; Meucin-24; Meucin-25; StCT1 |
4 | |
2011 | Vejovine; Ctriporin; Hp1090 | 3 | |
2012 | StCT2; HsAp1; VmCT1; VmCT2; AamAP2; BmKbpp |
7 | |
2013 | UyCT1; UyCT2; UyCT3; UyCT5; Css54; Pantinins 1–3; TsAP-1, TsAP-2; Hp1036; Hp1239 |
12 | |
2014 | Hp1404; Heterins 1 & 2; Spiniferin |
4 | |
2015 | AaeAP1; AaeAP2; Cm38; Stigmurin |
4 |
Data obtained from http://aps.unmc.edu/AP on May 15, 2015. The number of disulfide bonds, if there is any, is indicated between parentheses.