Table 3.
Amino acid sequences of selected antimicrobial peptides from spiders and scorpions1
| Species /structure |
Peptide name | Amino acid sequence | Length | Net charge |
Pho% |
|---|---|---|---|---|---|
| Spiders | |||||
| α | Cupiennin 1a | GFGALFKFLAKKVAKTVAKQAA KQGAKYVVNKQME |
35 | +8 | 48% |
| α | Latarcin 1 | SMWSGMWRRKLKKLRNALKK KLKGE |
25 | +9 | 36% |
| α | Latarcin 2a | GLFGKLIKKFGRKAISYAVKKA RGKH |
26 | +9 | 38% |
| α | Oxyopinin 4a | GIRCPKSWKCKAFKQRVLKRLL AMLRQHAF |
30 | +9 | 50% |
| α | LyeTx I |
IWLTALKFLGKNLGKHLAKQQL AKL |
25 | +6 | 52% |
| β | Gomesin | QCRRLCYKQRCVTYCRGR | 18 | +6 | 33% |
| β | Psalmopeotoxin I | ACGILHDNCVYVPAQNPCCRGL QCRYGKCLVQV |
33 | +3 | 48% |
| Scorpions | |||||
| α | IsCT | ILGKIWEGIKSLF | 13 | +2 | 53% |
| α | Meucin-13 | IFGAIAGLLKNIF | 13 | +2 | 69% |
| α | Pandinin 1 | GKVWDWIKSAAKKIWSSEPVSQ LKGQVLNAAKNYVAEKIGATPT |
44 | +4 | 40% |
| α | Pandinin 2 |
FWGALAKGALKLIPSLFSSFSKK D |
24 | +3 | 50% |
| α | Meucin-18 | FFGHLFKLATKIIPSLFQ | 18 | +2 | 55% |
| α | Meucin-24 | GRGREFMSNLKEKLSGVKEKMK NS |
24 | +4 | 25% |
| α | Ctriporin | FLWGLIPGAISAVTSLIKK | 19 | +3 | 57% |
| β | Androctonin | RSVCRQIKICRRRGGCYYKCTNR PY |
25 | +8 | 28% |
1
Data from the APD (http://aps.unmc.edu/AP). Peptide hydrophobic content is indicated with Pho%.