Table 5.
Amino acid sequence analysis of toxic helical peptides from spiders and scorpions1
| Organism | Spiders | Scorpions | ||
|---|---|---|---|---|
| Peptide group | 5 Short (24–28 aa) | 5 Long (35–48 aa) | 7 Short (13–24 aa) | 4 Long (44–47 aa) |
| Examples | Lycosin-I; Latarcins |
Oxyopinins | IsCT2, VmCT2, Meucin-13 |
Opistoporin 1, Parabutoporin |
| Average length |
26.6 | 39.2 | 15.8 | 45.0 |
| Pho% | 42.1% | 40.3% | 57.63% | 39.97% |
| Abundant hydrophobic residues |
L 10.5%; F 9%; A 9% |
L 8.2%; F 9.2%; A 10.2% |
I 13.5%; L 15.3%; F 15.3% |
L 8.3%; A 13.3%; I/V 11.1% |
| Net charge | +8.4 | +8.0 | +1.43 | +4.75 |
| Lysine% | 24.8% | 21.4% | 10.8% | 17.2% |
| Arginine% | 9.8% | 5.1% | 0% | 1.1% |
1
Only toxic peptides from the helical family were split into short and long groups and analyzed. Both peptide number and length are indicated for each group.