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Effect of systemic Ang II infusion on mTORC1 signaling in the SFO. Subcutaneous infusion of Ang II (1000 ng/kg · min) for 1 week (A) or 2 weeks (B) significantly increased the positive cell number of phosphorylated S6 (p-S6) in the SFO of wild-type mice. Microphotographs (×20 magnification) of phospho-S6 staining in the SFO and quantification data are displayed. Values are mean ± SEM, n = 5–8 per treatment; *, P < .05, t test.
