Table 2.
mEPSC Properties of AcbC MSNs Recorded From Prepubertal Male and Female Rats Exposed to Vehicle or Estradiol as Neonates
| mEPSC Property | Neonate Exposure | Male | Female | Statistics (F, P) |
|---|---|---|---|---|
| Frequency (Hz) | Vehicle | 1.57 ± 0.24 (12) | 2.37 ± 0.22 (15) | Interaction: 0.46, 0.50 |
| Estradiol | 1.16 ± 0.39 (7) | 1.61 ± 0.18 (17) | Sex: 6.42, 0.01 | |
| Hormone: 5.59, 0.02 | ||||
| Amplitude (pA) | Vehicle | 11.63 ± 0.31 (12) | 12.90 ± 0.52 (15) | Interaction: 0.01, 0.93 |
| Estradiol | 14.02 ± 1.13 (7) | 15.36 ± 0.81 (17) | Sex: 4.36, 0.04 | |
| Hormone: 8.84, 0.01 | ||||
| Decay (ms) | Vehicle | 2.94 ± 0.24 (12) | 3.75 ± 0.24 (15) | Interaction: 1.09, 0.30 |
| Estradiol | 3.17 ± 0.34 (7) | 3.98 ± 0.20 (17) | Sex: 11.29, 0.002 | |
| Hormone: 0.01, 0.91 |
Values are mean ± SEM. Numbers in parentheses indicate sample size. Data from animals unexposed to steroid sex hormones as neonates are located in Table 1. Select membrane properties analyzed in these experiments are presented in Results.