Table 2.
Trabecular Bone in Femur and Vertebrae L5 of POMC-ERα−/− Mice
| Control | POMC-ERα−/− | |
|---|---|---|
| Femur | ||
| BV/TV (%) | 12.2 ± 1.1 | 22.8 ± 2.8a |
| Tb.N (L/mm) | 2.9 ± 0.2 | 5.2 ± 0.6a |
| Tb.Th (μm) | 41 ± 1 | 44 ± 2 |
| Tb.Sp (μm) | 130 ± 1 | 115 ± 5a |
| Vertebrae L5 | ||
| BV/TV (%) | 21.1 ± 1.4 | 25.6 ± 2.6 |
| Tb.N (L/mm) | 4.9 ± 0.3 | 6.0 ± 1.1 |
| Tb.Th (μm) | 44 ± 2 | 44 ± 3 |
| Tb.Sp (μm) | 70 ± 3 | 62 ± 7 |
High-resolution μCT analyses of BV/TV, trabecular number (Tb.N), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp) in femur (n = 8–11) and vertebrae L5 (n = 4–7) of 6-month-old female POMC-ERα−/− and control mice. Data are presented as mean ± SEM.
a
P < .01, POMC-ERα−/− vs control mice, Student's t test.