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A, Cortical porosity at the midshaft femur was significantly increased by PTH in NTG mice, although post hoc tests yielded a significant increase only among oil-treated mice. Among TG mice, PTH increased cortical porosity significantly in both noninduced (oil-treated) and Cre-induced (tamoxifen-treated) mice. B, μCT reconstructions of the midshaft femur in TG mice, illustrating the changes in intracortical porosity resulting from tamoxifen and PTH treatments.
