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. 2016 Apr 20;311(1):C24–C34. doi: 10.1152/ajpcell.00295.2015

Fig. 9.

Fig. 9.

Knocking down ALK-5 attenuates PDGF-induced collagen synthesis and cell proliferation. PASMCs were transfected with ALK-5 siRNA or control siRNA and then incubated with PDGF-BB (10 ng/ml) for 24 h, after which collagen I protein level and cell proliferation were determined. A: representative immunoblots of collagen I from 4 experiments. B: bar graph showing the changes in protein levels of collagen I quantified by scanning densitometry. C: bar graph showing the changes in cell proliferation. Values are means ± SE; n = 4. *P < 0.05 vs. control. #P < 0.05 vs. control siRNA + PDGF.