Table 1.
Normal-Na+ Diet |
Low-Na+ Diet |
Post ANG II Infusion |
||||
---|---|---|---|---|---|---|
Day 2 |
Day 2 |
Day 2 |
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Control | KO | Control | KO | Control | KO | |
Food intake, g/day | 4.9 ± 0.4 | 4.4 ± 0.2 | 4.0 ± 0.3 | 3.8 ± 0.2 | 4.7 ± 0.3 | 5.1 ± 0.2 |
Water intake, ml/day | 3.6 ± 0.3 | 8.6 ± 0.8* | 3.9 ± 0.4 | 7.2 ± 0.8* | 7.2 ± 1.3 | 12.4 ± 0.5* |
Body weight, g | 28.0 ± 2.9 | 25.1 ± 1.4 | 26.3 ± 2.7 | 23.3 ± 1.4 | 24.1 ± 2.1 | 24.5 ± 0.9 |
Urine volume, ml/day | 1.4 ± 0.2 | 5.2 ± 0.8* | 1.3 ± 0.4 | 4.4 ± 0.7* | 4.7 ± 1.1 | 8.3 ± 0.3* |
Data are means ± SE. Knockout (KO) mice, n = 8–10 per group.
PRR, prorenin receptor.
P < 0.05 compared with control within each diet.