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. 2016 May 18;311(1):F71–F77. doi: 10.1152/ajprenal.00458.2015

Table 4.

Body weight as well as plasma DHT and estradiol levels in control and DHT-treated SS.5Bn and CYP4A2−/− female rats

SS.5Bn
CYP4A2−/−
Control DHT Control DHT
Body weight, g 269 ± 3 358 ± 11* 254 ± 9 384 ± 13*
DHT, pg/ml 27.29 ± 2.50 110.88 ± 5.67* 27.30 ± 2.68 101.82 ± 10.74*
Estradiol, pg/ml 9.54 ± 1.64 3.91 ± 0.85* 6.92 ± 0.73 4.40 ± 0.50*

n = 6–8 rats/group. CYP, cytochrome P-450.

*

P < 0.05 compared with controls of the same strain;

P < 0.05 compared with control SS.5Bn rats;

P < 0.05 compared with DHT-treated SS.5Bn rats.