Fig. 2.

The numbers of MDSCs (A), g-MDSCs (B), and m-MDSCs (C) recovered from the kidneys of healthy (black bars) vs. renal IRI (gray bars) CRPtg, WT, and CRP^−/− mice. Each bar and whisker represent the mean ± SE for n = 3–13 mice. The numbers of cells recovered (healthy vs. IRI) were compared using unpaired t-tests (2-tailed with Holm-Sidak correction), and when the difference was significant (P < 0.05) this is indicated with a double asterisk. The numbers of cells recovered from CRPtg and CRP^−/− vs. treatment-matched WT mice were compared using unpaired t-tests (1-tailed with Welch's correction), and when P < 0.05 this is indicated by ++.