Table 1.
Popliteal artery hemodynamics in control and fidgeting legs before, during, and after sitting for 3 h
| Duration of Sitting |
||||||
|---|---|---|---|---|---|---|
| Presit | 1 h | 2 h | 3 h | Postsit | ANOVA | |
| Basal diameter, cm | ||||||
| Control leg | 0.557 ± 0.02 | 0.585 ± 0.02 | 0.574 ± 0.02 | 0.589 ± 0.03 | 0.584 ± 0.03 | Time, P = 0.649 |
| Fidgeting leg | 0.571 ± 0.02 | 0.573 ± 0.02 | 0.573 ± 0.03 | 0.567 ± 0.02 | 0.562 ± 0.02 | Leg, P = 0.440 |
| Interaction, P = 0.183 | ||||||
| Blood flow, ml/min | ||||||
| Control leg | 71.75 ± 8.6 | 29.92 ± 4.5* | 27.26 ± 3.9* | 26.74 ± 3.5* | 50.75 ± 5.8* | Time, P = 0.027 |
| Fidgeting leg | 75.57 ± 8.5 | 38.00 ± 4.4* | 37.36 ± 3.4* | 38.39 ± 3.5*† | 61.19 ± 9.2 | Leg, P < 0.001 |
| Interaction, P = 0.855 | ||||||
| Hyperemic shear-rate AUC, arbitrary units | ||||||
| Control leg | 39,987 ± 5,135 | 21,679 ± 4,564* | Time, P = 0.026 | |||
| Fidgeting leg | 34,294 ± 7,182 | 24,785 ± 5,736* | Leg, P = 0.829 | |||
| Interaction, P = 0.579 | ||||||
| ANCOVA-corrected FMD, % | ||||||
| Control leg | 4.3 ± 0.9 | 1.8 ± 0.9 | Time, P = 0.635 | |||
| Fidgeting leg | 3.6 ± 0.9 | 6.8 ± 0.9† | Leg, P = 0.021 | |||
| Interaction, P = 0.004 | ||||||
| Mean arterial pressure, mmHg | 88 ± 2 | 94 ± 2* | 95 ± 2* | 94 ± 2* | 90 ± 1 | Time, P = 0.011 |
Values are means ± SE. Basal measurements of popliteal artery diameter and blood flow (in both legs) during sitting were performed after 2 min of rest following the 1-minute fidgeting. ANCOVA-corrected flow-mediated dilation (FMD) data are adjusted for hyperemic shear rate area under the curve (AUC).
*
P < 0.05 vs. presit;
†
P < 0.05, between legs.