Table 1.
iPSC-CM beating rate, percentage of cells beating, and shortening velocity at 1 and 2 wk after plating for N1 and M1
|
Week 1 |
Week 2 |
|||
|---|---|---|---|---|
| N1 | M1 | N1 | M1 | |
| BPM | 15.80 ± 3.63 | 10.77 ± 2.92a | 14.87 ± 5.28 | 13.80 ± 4.59 |
| N | 15 | 13 | 15 | 15 |
| % Cells beating | 89.67 ± 13.77 | 10.35 ± 8.84b | 77.87 ± 20.14 | 16.46 ± 7.98c |
| N | 8 | n = 8 | 4 | 4 |
| Shortening velocity, μm/s | 2.06 ± 0.65 | 0.93 ± 0.39d | 1.77 ± 0.47 | 1.80 ± 0.56 |
| N | 42 | 36 | 42 | 40 |
Values are means ± SD.
M1 or M2, mutant cell line number; N1 or N2, normal cell line number; BPM, beats per minute.
P < 0.001 vs. N1 (week 1), % cells beating:
P < 0.001 vs. N1 (week 1);
P < 0.001 vs. N1 (week 2); shortening velocity:
P < 0.001 vs. N1 (week 1).