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. 2016 May 27;311(1):H268–H275. doi: 10.1152/ajpheart.00175.2016

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Fig. 4. — Sensitivity of R-CEPIA1er at higher [Ca]_SR in rat ventricular myocytes. Representative line-scan images and corresponding profiles of R-CEPIA1er fluorescence in control conditions (left) and during application of isoproterenol (100 nM; right). Fragments of line-scan images are shown above the profiles (marked by gray boxes). The line scans are enlarged compared with the profiles. Myocytes were electrically stimulated at 0.75 Hz. When stimulation was stopped, caffeine (Caff, 10 mM) was applied to completely deplete [Ca]_SR.