Fig. 2.

Ca²⁺ sensitivity of tension and rate of tension redevelopment. A: Ca²⁺ sensitivity of tension in demembranated cardiac trabeculas from wild-type (WT) females (F) (n = 4) and HCM females (n = 6). B: Ca²⁺ sensitivity of tension in demembranated cardiac trabeculas from WT males (M) (n = 4) and HCM males (n = 6). C: rate of tension redevelopment (k_tr) in demembranated cardiac trabeculas from WT females (n = 4) and HCM females (n = 6). D: k_tr in demembranated cardiac trabeculas from WT males (n = 4) and HCM males (n = 6). k_tr plotted as a function of normalized tension; data plots represent binned values. Sarcomere length (SL) was set to 2.2 μm, and all data were normalized to saturating Ca²⁺ (maximum) tension.