Table 2.

Mean values of tension cost

	F-WT	F-HCM	M-WT	M-HCM
N	11	9	10	6
Tension cost, (pmol·s−1·mn−1·mm−1)	6.0 ± 0.4	4.3 ± 0.4	3.8 ± 0.5	6.0 ± 0.8*
Maximum hydrolysis, pmol·s−1·mm−3	318 ± 42	210 ± 27	258 ± 38	301 ± 35

Data are presented as means ± SE; n, no. of subjects. Tension cost was determined by the relationship between ATP hydrolysis and relative tension. Two-way ANOVA analysis revealed a strong interaction between sex and the HCM transgene with regard to tension cost. Bonferroni post hoc analysis found HCM males had a significantly higher tension cost compared with WT males. ATP hydrolysis at maximum tension was not different for any group.

^*P < 0.05 from WT counterpart.