Table 1.

Echocardiography data of control (lox/lox) and cardiomyocyte-specific TXNIP knockout mice

	lox/lox (n = 9)	cTKO (n = 6)
Left ventricular enddiastolic diameter (LVEDD), mm	3.99 ± 0.08	3.92 ± 0.11	NS
Left ventricular endsystolic diameter (LVESD), mm	2.75 ± 0.10	2.74 ± 0.16	NS
Left ventricular posterior wall thickness (LVPW), mm	1.06 ± 0.03	1.16 ± 0.07	NS
Left ventricular volume, diastolic (LV Vol; d), μl	71 ± 3	67 ± 5	NS
Left ventricular volume, systolic (LV Vol; s), μl	29 ± 2	29 ± 4	NS
Left ventricular ejection fraction (LV EF), %	60 ± 3	58 ± 4	NS
Left ventricular fractional shortening (LV FS), %	32 ± 2	30 ± 2	NS
Left ventricular cardiac output (LV CO), ml/min	21 ± 1	20 ± 1	NS

Numbers represent means ± SE. All mice analyzed were age-matched, 16–20 wk old males. All measurements were taken at heart rates >400 beats/min. cTKO, cardiomyocyte-specific TXNIP knockout mice; NS, not significant.