Table 1.

Expression of select genes implicated in vascular disease

	SOCS3+/+	SOCS3+/+	SOCS3+/−	SOCS3+/−
Gene	+ Vehicle	+ Ang II	+ Vehicle	+ Ang II
eNOS	1 ± 0.21	1.49 ± 0.33	0.33 ± 0.17*	0.54 ± 0.17
SOD1	1 ± 0.14	0.42 ± 0.13*	0.56 ± 0.12*	0.40 ± 0.14*
SOD2	1 ± 0.22	0.27 ± 0.07*	0.85 ± 0.05	0.34 ± 0.16
AT1-R	1 ± 0.27	3.44 ± 0.96	2.18 ± 0.36*	2.32 ± 0.35
IL-6	1 ± 0.28	23.97 ± 9.87*	0.92 ± 0.55	15.34 ± 6.06*†

Values are means ± SE. Gene expression in aorta from SOCS3^+/+ and SOCS3^+/− mice systemically treated with vehicle or angiotensin II (Ang II) for 14 days; n = 6,

^*P < 0.05 vs. vehicle.

^†P < 0.05 vs. SOCS3^+/− plus vehicle.