Background and Epidemiology

. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: Pediatr Clin North Am. 2016 Aug;63(4):567–584. doi: 10.1016/j.pcl.2016.04.001

Dornase alfa (Approved by the FDA in 1994)

High-dose ibuprofen

Inhaled tobramycin (1996)

Chronic azithromycin

Hypertonic saline

Inhaled aztreonam (2007)

Ivacaftor (2012)

Lumacaftor-ivacaftor (2015)

References 2–3, 69–74