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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Pediatr Clin North Am. 2016 Aug;63(4):617–636. doi: 10.1016/j.pcl.2016.04.003

Figure 2.

Figure 2

Figure 2

Pathophysiology of lung disease in CF. (a) Traditional view of pathology of lung disease in CF. Inflammation is triggered by chronic bacterial infection. (b) Potential alternative mechanism for airway inflammation in CF. Underlying CFTR dysfunction contributes to altered host-response.

From: Rao S and Grigg J, New insights into pulmonary inflammation in cystic fibrosis Arch Dis Child. 2006 Sep; 91(9): 786–788; with permission.