Table 1.
Host tissue, renal, and skeletal muscle blood flow and mean arterial pressure at rest and during exercise in tumor-bearing and sham-operated animals
| Ortho-Sham (n = 5) |
Ortho-TB (n = 4) |
|||
|---|---|---|---|---|
| Blood Flow, ml·100 g−1·min−1 | Rest | Exercise | Rest | Exercise |
| Bladder | 17.8 ± 1.2 | 17.2 ± 1.2 | 18.3 ± 2.0 | 17.8 ± 1.1 |
| Prostate | 29.4 ± 2.4 | 28.2 ± 2.5 | 33.0 ± 2.1 | 31.8 ± 1.3 |
| Soleus | 102.2 ± 14.7 | 190.3 ± 14* | 100.5 ± 15.1 | 176.4 ± 10.3* |
| Kidneys | 615 ± 25 | 449 ± 25* | 597 ± 32 | 488 ± 29* |
| MAP, mmHg | 114 ± 6 | 137 ± 6* | 118 ± 9 | 136 ± 13* |
| Ectopic-Sham (n = 5) |
Ectopic-TB (n = 6) |
|||
|---|---|---|---|---|
| Blood Flow, ml·100 g−1·min−1 | Rest | Exercise | Rest | Exercise |
| Skin | 9.3 ± 0.7 | 7.6 ± 0.4* | 10.2 ± 0.5 | 7.9 ± 0.4* |
| Subcutaneous adipose | 13.2 ± 1.1 | 4.7 ± 0.4* | 14.6 ± 1.2 | 5.1 ± 0.7* |
| Visceral adipose | 11.4 ± 0.6 | 5.3 ± 0.9* | 12.2 ± 1.2 | 4.4 ± 0.7* |
| Soleus | 92.4 ± 6.2 | 186.2 ± 7.8* | 91.5 ± 8.6 | 171.8 ± 4.0* |
| Kidneys | 566 ± 22 | 431 ± 23* | 550 ± 48 | 389 ± 38* |
| MAP, mmHg | 111 ± 4.2 | 130 ± 7* | 116 ± 4 | 129 ± 6* |
Values are means ± SE. MAP, mean arterial pressure.
*
P ≤ 0.05 vs. rest for same tissue. There was a trend for a greater mass-specific soleus muscle blood flow during exercise in the sham groups (P = 0.07 for Ortho-Sham; P = 0.06 for Ectopic-Sham) vs. corresponding tumor-bearing groups.