Table 2.
Isolated arteriole characteristics
| Sham-Operated Groups |
|||
|---|---|---|---|
| TB Group: Ectopic Tumor (n = 6) | Subcutaneous Adipose (n = 6) | Skin (n = 6) | |
| Maximal diameter, μm | 165 ± 12 | 180 ± 12 | 130 ± 10* |
| Wall thickness, μm | 12.7 ± 0.9 | 27.4 ± 1.3* | 24.0 ± 2.0* |
| Wall-to-lumen ratio | 0.08 ± 0.01 | 0.15 ± 0.01* | 0.19 ± 0.02*# |
| Tone, % | 11.2 ± 1.3 | 24.7 ± 1.3* | 29.0 ± 6.2* |
| EC50, [M] | 4.7 ± 1.9(e−7) | 5.9 ± 2.6(e−7) | 4.5 ± 3.5(e−6) |
| TB Group: Orthotopic Tumor (n = 6) | Sham-Operated Group: Prostate (n = 6) | |
|---|---|---|
| Maximal diameter, μm | 158 ± 13 | 181 ± 12 |
| Wall thickness, μm | 12.0 ± 1.0 | 18.8 ± 1.0* |
| Wall-to-lumen ratio | 0.07 ± 0.01 | 0.11 ± 0.01* |
| Tone, % | 9.1 ± 0.8 | 23.9 ± 4.9* |
| EC50, [M] | 8.0 ± 5.0(e−7) | 1.3 ± 1.1(e−6) |
Values are means ± SE.
*
P ≤ 0.05 vs. measurement in corresponding tumor (i.e., orthotopic tumor for prostate and ectopic tumor for subcutaneous adipose and skin). #P = 0.07 vs. measurement in subcutaneous adipose.