Table 2.

Pulmonary function

Measurement	Healthy Controls (n = 9)	Asthma (n = 19)	Between Groups t-Test P Value
Baseline
FEV1, % pred	91 ± 10.6%	77 ± 17%	0.03*
FVC, % pred	98 ± 10.7%	93 ± 15%	0.47
FEV1/FVC	0.78 ± 0.08	0.68 ± 0.12	0.05*
RV, % pred	102 ± 21%	155 ± 74%	0.07
FRC, % pred	124 ± 27%	129 ± 38%	0.77
TLC, % pred	102 ± 10%	108 ± 32%	0.60
RV/TLC	0.27 ± 0.09%	0.40 ± 0.12%	0.03*
Change after maximal relaxation with albuterol
% ΔFEV1	5 ± 5% (P = 0.17)	17 ± 11% (P < 0.0001)*	0.02*
% ΔFVC	−0.5 ± 2.2% (P = 0.97)	6 ± 6% (P < 0.0002)*	0.09
% ΔFEV1/FVC	6 ± 4% (P = 0.03)*	10 ± 8% (P < 0.0001)*	0.07
% ΔRV	4 ± 18% (P = 0.99)	−15 ± 24% (P = 0.01)*	0.21
% ΔFRC	−8 ± 8% (P = 0.18)	−9 ± 10% (P = 0.01)*	0.69
% ΔTLC	2 ± 3% (P = 0.73)	−5 ± 6% (P = 0.009)*	0.36
% ΔRV/TLC	2 ± 15% (P = 0.99)	−11 ± 20% (P = 0.07)	0.06

Values are means ± SD. P values within groups represent paired comparisons of baseline vs. postalbuterol maximum relaxation measurements using a mixed within-between groups ANOVA.

^*P < 0.05.