Table 1.
Lung function measured under anesthesia
| Pre-PNX |
Post-PNX |
|||
|---|---|---|---|---|
| SHAM | PAB | SHAM | PAB | |
| Number | 4 | 4 | 4 | 4 |
| Body weight, kg | 22.9 ± 1.0 | 18.5 ± 1.7* | 23.4 ± 0.6 | 19.7 ± 1.9*‡ |
| Hemoglobin while awake, g/dl | 13.3 ± 0.7 | 14.3 ± 0.5* | 13.3 ± 0.4 | 15.7 ± 1.4*‡ |
| Hemoglobin while anesthetized, g/dl | 11.8 ± 0.6 | 11.3 ± 0.4 | 12.3 ± 0.3‡ | 12.9 ± 0.7*‡ |
| End-expiratory lung volume, ml/kg | 41.5 ± 6.9 | 48.7 ± 6.6* | 35.7 ± 5.7‡ | 34.3 ± 2.6‡ |
| End-inspiratory lung volume, ml/kg | 79.7 ± 6.3 | 89.7 ± 8.3* | 72.7 ± 5.7‡ | 74.2 ± 4.1‡ |
| Specific lung compliance, ml·(cmH2O·l)−1 | 22.2 ± 5.0 | 22.2 ± 5.7 | 30.5 ± 6.9‡ | 26.2 ± 1.3 |
| Mean Pao2 during rebreathing, mmHg | 119.9 ± 3.9 | 119.9 ± 8.2 | 125.1 ± 1.5‡ | 118.8 ± 1.5* |
| Heart rate, beats/min | 152 ± 22 | 148 ± 17 | 133 ± 11‡ | 138 ± 10 |
| Pulmonary blood flow, ml/kg | 85.5 ± 13.1 | 90.5 ± 11.6 | 91.0 ± 11.9 | 85.2 ± 9.5 |
| DLCO-std, ml·(min·mmHg·kg)−1 | 0.67 ± 0.08 | 0.76 ± 0.13 | 0.43 ± 0.04‡ | 0.48 ± 0.03*‡ |
| DMCO, ml·(min·mmHg·kg)−1 | 1.13 ± 0.14 | 1.34 ± 0.41 | 0.70 ± 0.14‡ | 0.78 ± 0.20‡ |
| Pulmonary capillary blood volume, ml/kg | 2.46 ± 0.30 | 2.88 ± 0.49 | 1.84 ± 0.15‡ | 2.80 ± 1.92 |
| Septal tissue volume, ml/kg | 7.34 ± 1.54 | 6.39 ± 2.65 | 5.51 ± 1.15* | 5.39 ± 1.17 |
Values are means ± SD. PaO2, alveolar O2 tension. DLCO-std, DLCO adjusted to standard values of Hb = 14.6 g/dl and Pao2 = 120 mmHg. Inflation volume during rebreathing was 30 ml/kg. Specific compliance was calculated between 10- and 30-cmH2O transpulmonary pressure.
*
P ≤ 0.05 PAB vs. corresponding Sham banding by two-tailed unpaired t-test.
‡
P ≤ 0.05 pre-PNX vs. post-PNX by two-tailed paired t-test.