Table 4.
Absolute morphometric volumes and surface areas following right pneumonectomy
| Left Cranial Lobe |
Left Middle Lobe |
Left Caudal Lobe |
||||
|---|---|---|---|---|---|---|
| Sham | PAB | Sham | PAB | Sham | PAB | |
| Absolute volume, ml/kg | ||||||
| Septum† | 1.46 ± 0.47 | 1.14 ± 0.30 | 0.88 ± 0.26 | 0.53 ± 0.05* | 3.16 ± 0.95 | 2.00 ± 0.42# |
| Capillary blood† | 0.8490 ± 0.2828 | 0.6650 ± 0.1672 | 0.5101 ± 0.1636 | 0.3127 ± 0.0284* | 1.8428 ± 0.5330 | 1.2551 ± 0.3158 |
| Septal extravascular tissue† | 0.6117 ± 0.1922 | 0.4780 ± 0.1340 | 0.3715 ± 0.0981 | 0.2162 ± 0.0240* | 1.3169 ± 0.4183 | 0.7467 ± 0.1228* |
| Epithelium¥ | 0.1414 ± 0.0462 | 0.1256 ± 0.0328 | 0.0859 ± 0.0231 | 0.0538 ± 0.0119* | 0.2950 ± 0.1030 | 0.1928 ± 0.0471 |
| Type I¥ | 0.0831 ± 0.0248 | 0.0657 ± 0.0229 | 0.0466 ± 0.0159 | 0.0273 ± 0.0032* | 0.1877 ± 0.0622 | 0.1040 ± 0.0244* |
| Type II† | 0.2245 ± 0.0697 | 0.1913 ± 0.0544 | 0.1325 ± 0.0389 | 0.0811 ± 0.0133* | 0.4827 ± 0.1605 | 0.2969 ± 0.0643# |
| Interstitium§ | 0.2394 ± 0.0800 | 0.1674 ± 0.0458 | 0.1497 ± 0.0343 | 0.0797 ± 0.0142* | 0.5121 ± 0.1716 | 0.2531 ± 0.0176* |
| Endothelium† | 0.1443 ± 0.0412 | 0.1184 ± 0.0368 | 0.0889 ± 0.0265 | 0.0540 ± 0.0079* | 0.3164 ± 0.0884 | 0.2058 ± 0.0479# |
| Absolute surface area, cm2/kg | ||||||
| Alveolar surface† | 5,849 ± 2,178 | 4,338 ± 961 | 3,405 ± 953 | 1,983 ± 435* | 12,134 ± 4,080 | 8,052 ± 2,130 |
| Capillary surface | 5,797 ± 1,747 | 5,032 ± 1,241 | 3,341 ± 828 | 2,421 ± 339* | 12,837 ± 4,327 | 9,012 ± 2,024 |
Values are means ± SD.
*
P ≤ 0.05 and #P = 0.07, PAB vs. Sham banding in the same lobe by two-tailed unpaired t-test. ¥P = 0.07,
†
P ≤ 0.05, and §P ≤ 0.01, PAB vs. Sham banding across all lobes by repeated measures ANOVA.