Table 2.
Baseline and follow up PSG data in children with suspected ROHHAD
| Baseline PSG | Follow-up PSG | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pt | BMI (kg/m2) | Age (years) | PSG Diagnosis | SaO2 Min (%) | Co2 range (mmHg) | Treatment | • Time interval (years) • N of PSG |
BMI (kg/m2) | PSG diagnosis | CO2 range (mmHg) | Treatment |
| 1 | 35.7 | 4.7 | Mild OSA | 79 | 41–47 | Weight loss | • 1y 4 m | 43.5 | Severe OSA and NH | 50–54 | • Bi-Level PAP |
| • OAHI 3/h • CAI 0/h |
• 5 | • OAHI 12/h • CAI 0/h |
• Suppl. Oxygen (day) | ||||||||
| 2 | 28.5 | 9.0 | Mild OSA | 82 | 41–49 | Weight loss | • 2y 5 m | 36.4 | Moderate OSA and NH | 35–52 | Bi-Level PAP |
| • OAHI 4/h • CAI 0/h |
• 3 | • OAHI 9/h • CAI 0/h |
|||||||||
| 3 | 26.5 | 10.1 | Severe OSA | 83 | 29–38 | •Adenotonsillectomy • Weight loss |
• 6 m | 26.6 | Severe OSA and NH | 40–53 | • Bi-Level PAP |
| • OAHI 49/h • CAI 0/h |
• 1 | • OAHI 142/h • CAI 2.9/h |
• Oxygen (day and night) | ||||||||
| 4 | 40.7 | 8.3 | NH | 90 | 47–60 | Bi-Level PAP | • 8 m | 40.4 | No change | #32–39 | Maintained on Bi-Level PAP |
| • OAHI 0/h • CAI 0/h |
• 1 | • OAHI 0/h • CAI 0/h |
|||||||||
| 5 | 40.8 | 5.3 | Severe OSA and NH | 67 | 50–86 | Bi-Level PAP | - | - | • NOT PERFORMED | - | - |
| • OAHI 11/h • CAI 0/h |
• Pt deceased | ||||||||||
| 6 | 39.9 | 10.0 | Mild OSA | 81 | 38–44 | Weight loss | • 4y 8 m | 47.6 | Severe OSA and NH | Peak 51 | Bi-Level PAP |
| • OAHI 4/h • CAI 0/h |
• 8 | • OAHI 18/h • CAI 0/h |
|||||||||
Time Interval describes the time between the first and follow-up PSG in the table; Number of PSG refers to the total number of PSG that were performed between the first PSG and the follow-up PSG in the table; # - patient number 4 was not hypercapnic on follow-up PSG as this was undertaken on Bi-Level PAP
Abbreviations: OSA obstructive sleep apnea, NH nocturnal hypoventilation, OAHI obstructive apnea hypopnea index, CAI central apnea index, AT adenotonsillectomy