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. 2016 Jul 30;23:57. doi: 10.1186/s12929-016-0274-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — OxLDL-induced lipid accumulation and cell viability changes in human THP 1-derived macrophages. THP-1 macrophages were incubated with 80 ug/mL oxLDL for 0, 6, 24, 48, and 72 h. The intracellular lipid accumulation was determined by oil red staining and quantified with IPP software (a); (b) During the courses of foam cells formation and progress, cell viability was measured with MTT staining; (c) The data are expressed as means ± SD from at least 3 independent experiments. *P < 0.05 vs. 0 h. scale bars = 25 um