Table 5.
GM volume regions positively correlated with the score on the DMS-48 for the whole group of patients (group ABC) using VBM
Group (score) | P | Brain region | Side | BA | k | x | y | z | T |
---|---|---|---|---|---|---|---|---|---|
ABC (Set1), n = 138 | P = 0.001 | Hippocampus | R | NA | 606/1377 | 27 | –34 | –1 | 4.31 |
Parahippocampal g. | 28, 35–37 | 557/1377 | 28 | –39 | –6 | 4.36 | |||
Hippocampus | L | NA | 67/264 | –28 | –40 | 0 | 3.47 | ||
Parahippocampal g. | 19, 31 | 38/264 | –27 | –45 | –10 | 3.41 | |||
Precuneus | 31 | 70/70 | –2 | –71 | 21 | 3.43 | |||
ABC (Set2), n = 138 | P FWE = 0.05 | Hippocampus | R | NA | 370 | 28 | –37 | –3 | 5.42 |
Parahippocampal g. | 36–37 | 370 | 27 | –37 | –9 | 5.33 | |||
P = 0.001 | Hippocampus | R | NA | 1303/3820 | 30 | –25 | –12 | 4.65 | |
Parahippocampal g. | 19, 28, 35–37 | 834/3820 | 22 | –19 | –22 | 4.02 | |||
Hippocampus | L | NA | 94/279 | –25 | –39 | –3 | 3.67 |
Statistical analyses were performed including age, gender, education level, total GM volume and centre as nuisance covariate, with a threshold of P = 0.05, FWE or P = 0.001, uncorrected, including a minimal k of 50 voxels
GM grey matter, DMS-48, Delayed Matching-to-Sample—48 items, VBM voxel-based morphometry, L left, R right, BA Brodmann area, k cluster size in voxel (specific region’s volume/cluster’s global volume), x, y, z Talairach coordinates, T T value, g. gyrus, FWE family-wise error, Set1 immediate score, Set2 1-hour delayed score