Table 4.
Results of the target expression quantitative trait loci analysis.
| Gene Expression | Expression Quantitative Trait Loci | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||
| Probe ID | Chr | Gene Symbol | SNP | Chr | BP | Gene Symbol | Gene Location | Minor allele | Major all ele | MAF | Beta | P- value | q-value |
| ILMN_2226955 | 7 | VOPP1 | rs10228436 | 7 | 55238268 | EGFR | UTR3 | A | G | 0.3333 | 0.5988 | 0.0004 | 0.1404 |
| rs10277413 | 7 | 55238464 | EGFR | UTR3 | G | T | 0.3333 | 0.5988 | 0.0004 | 0.1404 | |||
| rs2275845 | 13 | 110823178 | COL4A1 | intronic | A | G | 0.08333 | −0.6839 | 0.0029 | 0.5349 | |||
| rs10492497 | 13 | 110831866 | COL4A1 | intronic | C | T | 0.08333 | −0.6839 | 0.0029 | 0.5349 | |||
| rs1000989 | 13 | 110827303 | COL4A1 | intronic | C | T | 0.3571 | −0.4762 | 0.0066 | 0.6672 | |||
| rs2017000 | 7 | 55242609 | EGFR | intronic | G | A | 0.25 | 0.4915 | 0.0079 | 0.6672 | |||
| rs148960146 | 10 | 121190174 | GRK5 | intronic | A | G | 0.07143 | 0.6584 | 0.0088 | 0.6672 | |||
| rs12721552 | 10 | 121199381 | GRK5 | intronic | A | G | 0.07143 | 0.6584 | 0.0088 | 0.6672 | |||
| rs143258813 | 21 | 35832052 | KCNE1 | intronic | GC | G | 0.05952 | −0.8223 | 0.0088 | 0.6672 | |||
| rs6599213 | 3 | 38617126 | SCN5A | intronic | A | G | 0.07143 | 0.6554 | 0.0091 | 0.6672 | |||
|
| |||||||||||||
| ILMN_2170625 | 2 | LOC389286 | rs36018953 | 20 | 1411595 | FKBP1A- SDCBP2, NSFL1C | intergenic | G | A | 0.08333 | 1.056 | 0.0007 | 0.5004 |
| rs1830519 | 6 | 161132830 | PLG | UTR3 | G | A | 0.3214 | 0.6561 | 0.0041 | 0.6380 | |||
| chr18:77228132 | 18 | 77228132 | NFATC1 | intronic | A | T | 0.2619 | 0.6026 | 0.0070 | 0.6380 | |||
| chr18:77228137 | 18 | 77228137 | NFATC1 | intronic | G | GC | 0.2619 | 0.6026 | 0.0070 | 0.6380 | |||
| chr18:77228152 | 18 | 77228152 | NFATC1 | intronic | A | T | 0.2619 | 0.6026 | 0.0070 | 0.6380 | |||
| chr18:77228154 | 18 | 77228154 | NFATC1 | intronic | GA | G | 0.2619 | 0.6026 | 0.0070 | 0.6380 | |||
| rs10228436 | 7 | 55238268 | EGFR | UTR3 | A | G | 0.3333 | −0.5993 | 0.0074 | 0.6380 | |||
| rs10277413 | 7 | 55238464 | EGFR | UTR3 | G | T | 0.3333 | −0.5993 | 0.0074 | 0.6380 | |||
| rs2289566 | 11 | 20117232 | NAV2 | exonic | C | T | 0.3452 | −0.6057 | 0.0078 | 0.6380 | |||
COL4A1: collagen, type IV alpha 1; EGFR: epidermal growth factor receptor; FAM126B: family with sequence similarity 126, member B; FKBP1A-SDCBP2, NSFL1C: FK506 binding protein 1A-syndecan binding protein (Syntetin) 2, NSFL1 (P97) Cofactor (P47); GRK5: G protein-coupled receptor kinase 5; KCNE1: potassium channel, voltage-gated subfamily E regulatory beta subunit 1; NAV2: neuron navigator 2; NFATC1: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; PLG: plasminogen; SCN5A: sodium channel, voltage gated, Type V alpha subunit; VOPP1: vesicular, overexpressed in cancer, prosurvival protein 1. (BP, base pair; Chr, chromosome; MAF, minor allele frequency; SNP, single-nucleotide polymorphism)