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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Gynecol Oncol. 2016 Apr;141(1):57–64. doi: 10.1016/j.ygyno.2016.01.004

Table 2. Multivariable Models for Overall Survival and Progression-Free Survival of BRCA wild type OvCa patients with different BRCAness status.

Overall Survival Progression-Free Survival
3-Year Rate, % (95% CI) 5-Year Rate, % (95% CI) HR (95% CI) P Value 3-Year Rate, % (95% CI) 5-Year Rate, % (95% CI) HR (95% CI) P Value
BRCAness
 Hypomutation 40(26-60) 15 (7-36) 1 [Reference] 8(2-27) 0* 1 [Reference]
 Intermediate 61(53-71) 34(16-35) 0.60(0.39-0.91) 0.016 16(10-26) 12(6-21) 0.80(0.53-1.21) 0.29
 BRCAness 75(56-100) 55(32-93) 0.33(0.15-0.69) 0.004 31(13-75) 21(6-68) 0.51(0.24-1.08) 0.077
Tumor Stage
 II 89(71-100) 67(36-100) 1 [Reference] 75(50-100) 37(9-100) 1 [Reference]
 III 59(51-68) 21(14-31) 2.34(0.73-7.43) 0.15 13(8-21) 8(4-16) 4.06(1.27-12.92) 0.018
 IV 48(33-70) 34(20-58) 2.40(0.71-8.08) 0.16 14(5-39) 14 (5-39) 4.22(1.25-14.22) 0.020
Age increase of 1.0 ye 1.02(1.00-1.03) 0.04 0.99(0.98-1.01) 0.34
*

all patients in the hypomutation group lived no more than 5-years