Table 3. Multivariable Models for Overall Survival and Progression-Free Survival of BRCA wild type OvCa patients with different RAD50 copy number status.
| Overall Survival | Progression-Free Survival | |||||||
|---|---|---|---|---|---|---|---|---|
| 3-Year Rate, % (95% CI) | 5-Year Rate, % (95% CI) | HR (95% CI) | P Value | 3-Year Rate, % (95% CI) | 5-Year Rate, % (95% CI) | HR (95% CI) | P Value | |
| RAD50 status | ||||||||
| RAD50 not deletion | 56 (48-64) | 22 (15-31) | 1 [Reference] | 13 (8-22) | 8 (4-17) | 1 [Reference] | ||
| RAD50 deletion | 69 (53-89) | 41 (24-70) | 0.44(0.25 -0.78) | 0.00 5 | 25 (12-52) | 20 (8-47) | 0.60(0.37-0.99) | 0.044 |
| Tumor Stage | ||||||||
| II | 89 (71-100) | 67 (36-100) | 1 [Reference] | 75 (50-100) | 38 (9-100) | 1 [Reference] | ||
| III | 59 (51-68) | 21 (14-31) | 2.63(0.83-8.30) | 0.100 | 13 (8-21) | 8 (4-16) | 4.15(1.31-13.12) | 0.016 |
| IV | 48 (33-70) | 34 (20-58) | 2.55(0.76-8.55) | 0.131 | 14 (5-39) | 14 (5-39) | 4.15(1.23-13.95) | 0.022 |
| Age increase of 1.0 ye | 1.02(1.00-1.04) | 0.011 | 0.99(0.98-1.01) | 0.523 | ||||