. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: Am J Obstet Gynecol. 2016 Mar 12;215(2):235.e1–235.e8. doi: 10.1016/j.ajog.2016.03.008

Table 2. Allele-based analysis comparing women with spontaneous preterm birth to women who delivered at term.

Gene	SNP	Minor Allele	Minor allele frequency		Odds Ratio	p	HWE^a
Gene	SNP	Minor Allele	Preterm	Term	Odds Ratio	p	HWE^a
PRETERM BIRTH <37 WEEKS
PRKCA	rs7225452	A	0.58	0.42	1.92	1.2ˆ10^-4	Yes
PRKCA	rs4486944	C	0.62	0.47	1.79	7.0ˆ10^-4	Yes
PRKCA	rs6504424	A	0.61	0.47	1.82	5.8ˆ10^-4	Yes
PRKCA	rs16960070	A	0.12	0.05	2.45	6.3ˆ10^-4	Yes
PRETERM BIRTH <34 WEEKS
FLT1	Rs12428494	A	0.11	0.03	3.81	3.7ˆ10^-4	Yes

Based on frequencies of the alleles in the entire cohort