. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: Am J Obstet Gynecol. 2016 Mar 12;215(2):235.e1–235.e8. doi: 10.1016/j.ajog.2016.03.008

Table 3. Single SNPs genotype-based analyses for spontaneous preterm birth <37 weeks.

Gene	SNP	Model	OR	p	aOR^a	p	HWE^b
MMP2	rs11639960	Recessive	8.26	4.8ˆ10^-5	9.10	2.6ˆ10^-5	No
TIMP 2	rs2277698	Recessive	8.70	4.7ˆ10^-4	8.44	6.8ˆ10^-4	Yes
IL1 6	rs7171517	Dominant	2.31	5.8ˆ10^-4	2.26	8.6ˆ10^-4	Yes
PRKCA	rs16960070	Dominant	2.84	3.2ˆ10^-4	3.02	1.7ˆ10⁴	Yes
PRKCA	rs7225452	Additive	1.92	1.7ˆ10^-4	1.98	1.2ˆ10^-4	Yes
PRKCA	rs6504424	Additive	1.84	6.4ˆ10^-4	1.90	4.8ˆ10^-4	Yes
PRKCA	rs4486944	Additive	1.79	8.5ˆ10^-4	1.86	5.4ˆ10^-4	Yes

Adjusted for prior preterm birth

Based on frequencies of the alleles in the entire cohort