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. Author manuscript; available in PMC: 2016 Jul 30.
Published in final edited form as: J Immunol. 1999 Aug 15;163(4):2187–2192.

FIGURE 3.

FIGURE 3

Immunochemical analysis of chondrocytes exhibiting suppression of rhIL-1β-dependent iNOS synthesis by CTS. The iNOS synthesis in chondrocytes was compared in cells subjected to medium alone (A), CTS alone (B), rhIL-1β (C) (1 ng/ml), or costimulation with CTS and IL-1β (D) for 24 h. Histomorphometric analysis of cells showed absence of iNOS in A and B. IL-1β-treated cells (C) show presence of iNOS by intense peroxidase staining in 35 ± 4% of chondrocytes, while cells subjected to simultaneous IL-1β and CTS (D) showed a 62 ± 6% lower staining intensity for iNOS, as compared with iNOS-positive cells in C.