Table 3.
List of macrophage genes whose activity changes in the accumulation of intracellular cholesterol.
| Gene | Molecule | Functions |
|---|---|---|
| FCGBP | Fc fragment of IgG binding protein | Immune response |
| S100A8 | S100 calcium binding protein A8 | Immune response, migration, cell body formation |
| ITLN1 | Intelectin 1 (galactofuranose binding) | Pathogen metabolism |
| NCOR2 | Nuclear receptor corepressor 2 | Immune response |
| TPPP3 | Tubulin polymerization-promoting protein family member 3 | Cell body formation |
| AKR1C1 | Aldo-keto reductase family 1, member C1 | Immune response |
| FAM65A | Family with sequence similarity 65, member A | Cell body formation |
| HECTD2 | HECT domain containing E3 ubiquitin protein ligase 2 | Metabolism |
| RD3 | Retinal degeneration 3 | Nerve features |
| TNFSF18 | Tumor necrosis factor (ligand) superfamily, member 18 | Immune response, migration |
| NEURL3 | Neuralized E3 ubiquitin protein ligase 3 | Metabolism |
| CD209 | CD209 molecule | Immune response, migration, dendritic cell features |
| STRIP2 | Striatin interacting protein 2 | Cell body formation |
| CCL4L2 | Chemokine (C-C motif) ligand 4-like 2 | Migration |
| TJP2 | Tight junction protein 2 | Migration |
| SPON2 | Spondin 2, extracellular matrix protein | Migration |
| L1CAM | L1 cell adhesion molecule | Migration |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | Migration |
| NES | Nestin | Cell body formation, nerve features |
| F3 | Coagulation factor III (thromboplastin, tissue factor) | Migration |
| GALNT5 | Polypeptide N-acetylgalactosaminyltransferase 5 | Metabolism |
| MT1E | Metallothionein 1E | Metabolism |
| COQ2 | Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | Metabolism |
| TRIM54 | Tripartite motif containing 54 | Cell body formation |
| ANKRD63 | Ankyrin repeat domain 63 | Cell body formation |
| CCL24 | Chemokine (C-C motif) ligand 24 | Immune response, migration |
| HIVEP3 | Human immunodeficiency virus type I enhancer binding protein 3 | Immune response |
| NETO2 | Neuropilin (NRP) and tolloid- (TLL-) like 2 | Nerve features |
| CCL4 | Chemokine (C-C motif) ligand 4 | Immune response, migration |
| ACPP | Acid phosphatase, prostate | Metabolism |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | Metabolism |
| RANBP10 | RAN binding protein 10 | Cell body formation |
| ROBO2 | Roundabout guidance receptor 2 | Migration, nerve features |
| CHL1 | Cell adhesion molecule L1-like | Migration, nerve features |
| RARA | Retinoic acid receptor, alpha | Negative regulation of interferon-gamma production; positive regulation of interleukin-4 production, immune response |
| SLC16A9 | Solute carrier family 16, member 9 | Metabolism |
| HTR2A | 5-Hydroxytryptamine (serotonin) receptor 2A, G-protein-coupled | Nerve features |
| BCAR1 | Breast cancer antiestrogen resistance 1 | Migration |
| OR6K3 | Olfactory receptor, family 6, subfamily K, member 3 | Nerve features |
| CYP7B1 | Cytochrome P450, family 7, subfamily B, polypeptide 1 | Metabolism |