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. 2016 Aug;24(8):1376–1383. doi: 10.1016/j.joca.2016.03.004

Table IV.

Associations between effusion and synovial hypertrophy with pain

Author, year Sample size Mean age (SD/range) Proportion of women Standardised quality score (% of the maximum score) Association between effusion and pain Association between synovial hypertrophy and pain
Bevers 2014 180 57 (9.2) 66.7 50 No association No association
Song 2008 41 65 (6.7) 63.4 22.2 No association No association
Ulasli 2014 86 56.2 (10.2) 80.2 60.0 No association
Hall 2014 62 73.9 (7.8) 67.7 55.6 Positive association Positive association
D'Agostino 2005 600 66.7 (9.8) 72.5 90.0 Positive association No association
Malas 2014 61 58.88 (7.2) 83.6 40.0 Positive association
Mendieta 2006 101 62.1 (9) 70.0 70.0 Positive association with pain on motion
Chan 2014 193 59 (13.9) 74.1 60.0 Positive association with pain on walking, but not while sitting Positive association with pain while sitting, but not walking
Wu 2012 56 62.9 (8.2) 75.0 66.7 Positive association with pain during movement, but not at rest No association with pain on movement and at rest
Naredo 2005 50 64.3 (7.9) 88.0 55.6 Positive association with pain during movement and at rest
% positivity 7/10 2/6

Adjusted for radiographic severity.