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HPLC chromatograms of (A) SVA spiked into Dulbecco's modified eagle medium (pH 7.4) with internal standard (IS = 4,4-dichlorodiphenyltrichloroethane), (B) SVL spiked into Dulbecco's modified eagle medium (pH 7.4) with internal standard (IS = 4,4-dichlorodiphenyltrichloroethane), (C) blank culture medium. SVA, simvastatin hydroxy acid; SVL, simvastatin lactone; IS, internal standard.
