Table 1.
Summary of Disease Phenotypes in Mll-AF4-Expressing Mice
| Mouse ID | Splenomegaly | Mesenteric Disease | Mediastinal Disease | BM | Peripheral Blood | Liver | Disease |
|---|---|---|---|---|---|---|---|
| Mll-AF4 × Vav-Cre (Median Survival 556 Days) | |||||||
| 3809 | √ | – | √ | √ | – | √ | T cell lymphoma |
| 4468 | √ | √ | – | – | – | √ | B cell lymphoma |
| 4475 | √ | – | – | – | – | √ | B cell lymphoma |
| 4649 | √ | √ | – | – | – | √ | B cell lymphoma |
| 4650 | √ | √ | – | – | – | √ | B cell lymphoma |
| 5244 | √ | √ | – | – | – | – | B cell lymphoma |
| 5250 | √ | – | – | – | – | √ | B cell lymphoma |
| 5909 | √ | – | – | – | – | √ | B cell lymphoma |
| 5911 | √ | √ | – | √ | √ | √ | T cell lymphoma |
|
Mll-AF4 × VEC-Cre (Median Survival 437 Days) | |||||||
| 6357 | √ | – | – | – | – | √ | lymphoproliferative disorder |
| 6703 | √ | √ | – | – | – | √ | lymphoproliferative disorder |
| 6705 | √ | √ | – | – | – | √ | B cell lymphoma |
| 6707 | √ | √ | – | – | – | √ | B cell lymphomaa |
| 6709 | √ | √ | – | – | – | √ | B cell lymphoma |
| 6713 | √ | – | – | – | √ | √ | lymphoproliferative disorder |
| 6809 | √ | √ | – | – | – | √ | B cell lymphoma |
| 6810 | √ | √ | – | – | – | √ | B cell lymphoma |
| 7060 | √ | √ | – | – | – | √ | B cell lymphoma |
| 7063 | √ | √ | √ | – | – | √ | B cell lymphoma |
| 7737 | √ | √ | √ | – | – | √ | T cell lymphoma |
| 7739 | √ | √ | √ | – | – | √ | B cell lymphoma |
| 8945 | √ | √ | – | – | – | – | B cell lymphoma |
| 0062 | √ | – | – | – | – | √ | B cell lymphoma |
a
Transplanted.