Table 2.

Effect of lycopene and sodium valproate on GABA, SOD, and catalase levels in pentylenetetrazol-induced changes in the brain tissue

S. No.	Groups	GABA (ng/g of brain tissue)	SOD (IU/mg protein)	Catalase (nmol H2O2 consumed/min/mg protein)	P value
1	Normal Control	32.25±1.23	42.34±1.31	12.15±1.11
2	PTZ Control	8.286±1.46a	21.57±1.91a	6.84±0.28a	0.009
3	SVP+PTZ	28.27±1.16b	34.12±1.23b	11.35±0.92b	0.049
4	LYC2+SVP+PTZ	29.32±1.19c	39.42±2.17c	12.13±1.27c	0.009
5	LYC4+SVP+PTZ	31.21±1.20d	45.36±2.21c	14.24±1.63d	0.008

GABA: Gamma-aminobutyric acid; SOD: Superoxide dismutase activity. Data are expressed as mean±SEM.

^aP<0.01 versus control;

^bP<0.05;

^cP<0.01 versus the PTZ control