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. Author manuscript; available in PMC: 2017 Jun 22.
Published in final edited form as: Cell Syst. 2016 Jun 16;2(6):402–411. doi: 10.1016/j.cels.2016.05.006

Figure 2. Cell-stiffness modulators encompass a large range of cellular functions.

Figure 2

A) Maximal growth rates in liquid and agarose. Blue and red ovals represent the mean growth rates ± one standard deviation for BW25113 and ΔmrcB, respectively (n ≥ 5 independent experiments); the gray oval represents the distribution of values for the Keio collection.

B) The 46 genes with GRABS score < −0.15 (n = 41) or > 0.3 (n = 5) come from 18 Clusters of Orthologous Groups (COGs). Several genes (ΔrecA, ΔtolR, ΔtolB, ΔwcaG, ΔfliA) are assigned to two or more orthologous groups, which gives rise to n = 53 total assignments.

C) Top: distribution of GRABS scores. Bottom: GRABS hits in (B). The average GRABS score and standard deviation across ≥ 6 replicates from multiple independent experiments are shown. Genes are colored according to their COG assignment. Genes with ≥ 2 COG assignments are colored accordingly. E. coli BW25113 has a GRABS score of 0 by definition.