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. Author manuscript; available in PMC: 2016 Jul 31.
Published in final edited form as: Transl Stroke Res. 2012 Nov 15;4(1):25–39. doi: 10.1007/s12975-012-0226-1

Fig.1. Schematic representation of the effect of preconditioning in traumatic brain injury (TBI).

Fig.1

In the upper part of the illustration, the main pathomechanisms responsible for the injurious cascade after TBI are represented, which can result in different kind of brain damage and adversely affect neurologic outcome.

In the lower part of the figure, preconditioning strategies applied before TBI, acting alone or in combination, result in the phenomenon of preconditioning, which may reduce the extent of subsequent brain damage and result in improved neurologic outcome.