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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Anal Bioanal Chem. 2016 Mar 4;408(13):3453–3474. doi: 10.1007/s00216-016-9421-3

Fig. 8.

Fig. 8

Integrated analysis of glycerophospholipid biosynthesis. LC-MS proteomic data revealed downregulation of lysophosphatidylcholine acyltransferase (LPCAT) and lipid phosphate phosphohydrolase in Sp2-cKO mice. Imaging MS data demonstrated a direct correlation with proteomic data with a downregulation of LPCAT products phosphocholine and phosphatidic acid while the subsequent metabolite, phosphatidylglycerol, was found to be upregulated in Sp2-cKO mice. KEGG glycerophospholipid metabolism (http://www.genome.jp/kegg/pathway/map/map00564.html)