Figure 4.

Capacity of bone marrow mononuclear cells (BM-MNC) from the 8 donors to generate mesenchymal stromal cells (MSC), their proliferation potential and chimeric analysis of the MSC end-products (MEP). (A) Data are expressed as the number of generated MSC per 1×10⁶ BM-MNC from each donor cultured in 5% human platelet lysis (PL) for 13 days. Age of each donor (in years) is shown in brackets. (B) Comparison of the proliferation potential of MSC from the 8 individual donors with that of pooled MSC from the 8 individual donors and four MEP. (C) Determination of the relative proportion of each donor in MEP via STR-PCR; ns: not significant. Statistical analysis was performed using Student’s t-test.