Table 5.
Genotype frequencies in anti-CCP positive rheumatoid arthritis, relative to anti-CCP negative
| Anti-CCP+ (n = 80) | Anti-CCP– (n = 25) | χ2 | p | Odds ratio 95% CI | |
|---|---|---|---|---|---|
| SNPs | |||||
| TNFAIP3 rs2203926 | |||||
| T/T No. (%) | 57 (71.3%) | 21 (84.0%) | |||
| G/T No. (%) | 20 (25.0%) | 4 (16.0%) | 1.043 | 0.307 | 1.842 (0.564-6.021) |
| G/G No. (%) | 3 (3.8%) | 0 (0.0%) | – | – | – |
| G allele No. (%) | 26 (16.25%) | 4 (8.0%) | 2.117 | 0.146 | 2.231 (0.739-6.735) |
| TRAF1 rs10181488 | |||||
| G/G No. (%) | 2 (2.5%) | 25 (100.0%) | – | – | – |
| A/G No. (%) | 57 (71.3%) | 0 (0.0%) | – | – | – |
| A/A No. (%) | 21 (26.3%) | 0 (0.0%) | – | – | – |
| A allele No. (%) | 99 (61.9%) | 0 (0.0%) | – | – | – |
Qualitative data are expressed using the number and percent and compared using χ2.
* statistically significant at p ≤ 0.05