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. 2016 Jul 15;41(2):165–175. doi: 10.5114/ceji.2016.60991

Genotype frequencies with SLE severity

Mild to moderate flare (n = 36) Severe flare (n = 54) χ2 p Odds ratio 95% CI
SNPs
TNFAIP3 rs2203926
 T/T No. (%) 24 (66.7%) 42 (77.8%)
 G/T No. (%) 12 (33.3%) 9 (16.7%) 2.836 0.092 0.429 (0.158-1.164)
 G/G No. (%) 0 (0.0%) 3 (5.6%)
G allele No. (%) 12 (15.4%) 15 (14.7%) 0.016 0.899 0.948 (0.416-2.161)
TRAF1 rs10181488
 G/G No. (%) 12 (33.3%) 27 (50.0%)
 A/G No. (%) 24 (66.7%) 21 (38.9%) 4.344* 0.037* 0.389 (0.159-0.954)
 A/A No. (%) 0 (0.0%) 6 (11.1%)
A allele No. (%) 24 (30.8%) 33 (32.4%) 0.051 0.821 1.076 (0.570-2.031)