Table 1.
Testing modalities for diagnosing HIV in pregnancy∗.
HIV tests | What they test for | Window period | Available results | Sensitivity | Specificity |
---|---|---|---|---|---|
ELISA | HIV antibodies | 3 Months | 2 days–2 weeks | >99% | >98% |
Antigen test (p24) | P24 viral proteins | 11 days–1 month | 2 days–1 week | 90% | 100% |
4th generation tests | Antibodies and p24 | 11 days–1 month | 2 days–2 weeks | >99.7% | >99.3% |
PCR/NAAT tests | Genetic material of HIV | 12 days | 2 days–1 week | >99% | >99% |
Rapid test | Antibodies | 3 Months | Within 20 minutes | >99% | >98% |
∗AIDSinfo. Recommendations for use of antiretroviral drugs in pregnant HIV-1-infected women for maternal health and interventions to reduce perinatal HIV transmission in the United States. HHS panel on treatment of HIV-infected pregnant women and prevention of perinatal transmission, a working group of the office of AIDS research advisory council (OARAC), 2015, http://aidsinfo.nih.gov/guidelines.