Table 1.
Proportions of α- and δ-cells in small and big islets. Areas stained for glucagon and somatostatin in the largest cross section of small (<60 µm) and big (>100 µm) islets. The data refer to observations made in paraffin sections of pancreas and isolated islets. All values are given as means ± SEM. ∗ P < 0.001 compared with small islets stained for glucagon in the pancreas. # P < 0.05 compared with small islets stained for somatostatin in the pancreas. † P < 0.05 compared with small isolated islets stained for glucagon. ¤ P < 0.001 compared with small isolated islets stained for somatostatin.
Islets in pancreas | Isolated islets | |||
---|---|---|---|---|
Small islets | Big islets | Small islets | Big islets | |
Glucagon | ||||
Number of animals | 5 | 5 | 6 | 4 |
Number of islets | 52 | 65 | 52 | 44 |
Area stained for glucagon (%) | 3.22 ± 0.51 | 8.61 ± 0.50∗ | 0.1 | 1.43 ± 0.28† |
| ||||
Somatostatin | ||||
Number of animals | 5 | 5 | 4 | 5 |
Number of islets | 68 | 51 | 35 | 50 |
Area stained for somatostatin (%) | 4.60 ± 0.48 | 3.37 ± 0.22# | 5.71 ± 0.58 | 3.54 ± 0.24¤ |